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Histopathology

Histopathology refers to the microscopic examination of tissue in order to study the manifestation of disease. Cancer management entails a multidisciplinary approach involving specialists from several different fields.

The histopathologist establishes a definitive cancer diagnosis and provides the clinical colleagues with information they require to deliver optimized care. Histopathology reports today give detailed information and the diagnosis includes immunohistochemistry and even molecular findings.

Types of samples received include

  • Incisional biopsy – diagnostic biopsies from any site
  • Excisional biopsy – Small Tumors
  • Punch biopsy e.g. Oral Cavity, GIT, etc.
  • Core needle biopsy e.g. breast
  • Curettage biopsy e.g. endometrium
  • Radical excision specimens e.g. mastectomy, neck dissections, colectomy, etc.

Grossing

  • Refers to the detailed description of the surgical specimen by the histopathologist where weight, size measurements and gross descriptions are given.
  • If it is a resection specimen inking of margins is done.

Histopathological techniques

They deal with the preparation of tissue for microscopic examination after grossing of the specimen. These processes are

  • Fixation
  • Dehydration
  • Clearing
  • Embedding
  • Cutting
  • Staining

Immunohistochemistry

  • Immunohistochemistry has become a useful tool in surgical pathology not only for diagnoses but also for prognostication and therapy of certain tumors.
  • Examples: Her2 for breast cancer, CD 117 for GIST, MIB1 for neuroendocrine tumor and CD markers for lymphomas.

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102, 1st Floor, Sanoma Plaza, Opp. Parimal Garden, Besides JMC House, Ellisbridge, Ahmedabad - 380006.

Mobile :  +91 95588 00100
Telephone :  +91 (79) 2646 8485
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Fax :  +91 (79) 400 22 804

E-mail :  info@unipath.in
Web :  www.unipath.in